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D-optimal designs for drug synergy.
This thesis is fo cused on the construction of optimal designs for detecting drug interaction using the two-variable binary logistic mo del. Two sp eci c mo dels are considered: (1) the binary two-variable logistic mo del ...
Analysis of longitudinal binary data : an application to a disease process.
The analysis of longitudinal binary data can be undertaken using any of the three families of models namely, marginal, random effects and conditional models. Each family of models has its own respective merits and demerits. ...