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Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.

Abstract

Abstract available in pdf.

Description

CAPRISA, 2014.

Keywords

Antibodies, Neutralizing/chemistry., Antibodies, Neutralizing/genetics., Antibodies, Neutralizing/immunology., CD4-Positive T-Lymphocytes/immunology., HIV Antibodies/chemistry.

Citation

Kepler, T.B., Liao, H.X., Alam, S.M., Bhaskarabhatla, R., Zhang, R., Yandava, C., Stewart, S., Anasti, K., Kelsoe, G., Parks, R., Lloyd, K.E., Stolarchuk, C., Pritchett, J., Solomon, E., Friberg, E., Morris, L., Abdool Karim, S.S., Cohen, M.S., Walter, E., Moody, M.A., Wu, X., Altae-Tran, H.R., Georgiev, I.S., Kwong, P.D., Boyd, S.D., Fire, A.Z., Mascola, J.R., and Haynes, B.F. 2014. Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. Cell host & microbe 16(3), 304-313.

DOI