Now showing items 1-10 of 17
Phytochemical and anti-drepanocytosis studies of Cajanus cajan, Callistemon viminalis, Melaleuca bracteata var. Revolution Gold and Syzygium guineense.
All over Africa, traditional healers use medicinal plants to prepare medicines to treat a wide range of illnesses. One of these illnesses is sickle cell anaemia or drepanocytosis or sicklemia. This disease is particularly ...
Structural and synthetic studies of sesquiterpenoids and flavonoids isolated from Helichrysum species
The genus Helichrysum (Asteraceae) consists of approximately 500 species worldwide, with 245 indigenous to South Africa. As a result of the large number of species, the chemistry and biological activity of several species ...
Approaches to the total synthesis of a novel diarylheptanoid
The total synthesis of a novel diarylheptanoid isolated from a South African medicinal plant, Siphonochilus aethiopicus, was investigated. S. aethiopicus (Indungulu in Zulu) is the only South African species of the ...
Structure and synthesis of Phloroglucinol derivatives from Hypericum roeperianum
The research presented in this study combines natural product chemistry with organic
The discovery and characterization of antiprotozoal compounds from South African medicinal plants by a HPLC-based activity profiling technique.
A total of 507 plant extracts from 174 South African plant species, selected based on their traditional uses against parasitic diseases, mainly against malaria were screened against Plasmodium falciprum, Trypanosoma ...
Bioactive sesquiterpenoids from dicoma anomala subsp. gerrardii
Through South Africa’s first collaborative project between a large scientific organisation, the Council for Scientific and Indust rial Research (CSIR), and the Traditional Healer’s Committee, Dicoma anomala was identified ...
Towards the total synthesis of a novel diarylheptanoid.
Diarylheptanoids are a family of plant metabolites with a characteristic structure of two hydroxylated aromatic rings attached by a linear seven-carbon chain. Diarylheptanoids have mostly been isolated from plants belonging ...
Antidiabetic compounds from Hypoxis colchicifolia and Terminalia sericea.
In this project two medicinal plant species, namely Hypoxis colchicifolia Bak (Hypoxidaceae) and Terminalia sericea Burch. (Combretaceae), have been investigated and different compounds isolated and characterised. The aim ...
Structure and synthesis of Gunnera perpensa secondary metabolites.
The project focused on the isolation, characterization and synthesis of secondary metabolites of Gunnera perpensa L. (Gunneraceae), a South African medicinal plant used by many South African women to induce or augment ...
Synthesis of prenylated benzoquinones.
The research presented in this study demonstrates the critical role that organic synthesis plays in natural product chemistry. The biological activity demonstrated by 2-methyl-6-(3-methyl-2- butenyl)benzo-1,4-quinone ...