Now showing items 1-10 of 48
HIV epidemic types and customized prevention responses.
Since the first reported case of AIDS 27 years ago, more than 70 million people have been infected with HIV worldwide, and 25 million have died of AIDS. The Joint United Nations Programme on HIV/AIDS (UNAIDS) estimates ...
An investigation into the effects of Sutherlandia Frutescens, L-Canavanine and aflatoxin B1 in the HepG2 human hepatocarcinoma cell line.
Aflatoxin B1 (AFB1), a potent hepatotoxic and hepatocarcinogenic mycotoxin synthesised by toxigenic fungi (Aspergillus flavus and Aspergillus parasiticus), is a common contaminant of many cereal commodities consequently ...
An in vivo study to determine the effects of Ochratoxin A and Sutherlandia frutescens in male Wistar rats.
Ochratoxin A (OTA), a nephrotoxic mycotoxin, is a contaminant of several agricultural food products consumed by animals and humans. Apart from renal toxicity, in particular renal tumours, OTA may also result in teratogenicity, ...
The effects of Sutherlandia frutescens in cultured renal proximal and distal tubule epithelial cells.
Sutherlandia frutescens (SF), an indigenous medicinal plant to South Africa (SA), is traditionally used to treat a diverse range of illnesses including cancer and viral infections. The biologically active compounds of SF ...
An investigation into the chemopreventive properties of an indigenous herb, Amaranthus lividus, using cancerous cell lines.
Chemoprevention may be defined as the inhibition, delay or reversal of carcinogenesis by dietary compounds or their derivatives. "Imifino" is a collective name for many wild plants used predominantly by rural people as ...
The effect of ultradistance running on premenopausal women of different ethnic groups.
No abstract available.
The case for critical thought : an investigation into contemporary determinist knowledge, its social effects, and the alternative offered by a 'mode 2' approach to teaching, learning and research.
This thesis is centrally concerned with the current nee-liberal world order and its effects upon society. It is concerned to expose the contradictions and weaknesses within the knowledge systems that underpin our political ...
The possible implication of selected Fusarium Mycotoxins in the aetiology of brain cancer.
The central nervous system is a potential site of action for the Fusarium mycotoxin Fumonisin B1 (FB1), and is exemplified in horses by the disease equine leukoencephalomalacia. Structurally resembling sphingoid bases, FB1 ...
A microsatellite evaluation of the genetic status of the p27Kip1 and p21Cip1/WAF1 genes in oesophageal cancer.
p21 C/P 1/"El and p 2 7K/P 1 are cyclin-dependant kinase inhibitors that fonn an integral part of the cell cycle process. These proteins function as cell-cycle inhibitors, and are able to induce cell cycle arrest by binding ...
The cytotoxic effects of deoxynivalenol and fumonisin B1 on the HT-29 human colonic adenocarcinoma cell line.
The human population can be considered as a subject of combined exposure to chemicals against which the gastrointestinal tract represents the first barrier. The most relevant are those compounds that occur in plants which ...