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Molecular modeling studies on HIV-1 Reverse Transcriptase (RT) and Heat shock protein (Hsp) 90 as a potential anti-HIV-1 target.
(2015)
Human immunodeficiency virus (HIV) infection is the leading cause of death globally. This dissertation addresses two HIV-1 target proteins namely, HIV-1 Reverse Transcriptase (RT) and Heat shock protein (Hsp) 90. More ...
Effects of a resistance exercise intervention programme on body composition, chronic disease risks and strength scores in people living with HIV and Aids (PLWHA) receiving antiretroviral therapy (ART) in Zimbabwe.
(2017)
Introduction
People living with HIV and AIDS (PLWHA) receiving antiretroviral therapy (ART) increases their life
expectancy. Receiving ART coupled with physical inactivity results in increase in prevalence of
hyperlipidaemia, ...
Immunological effects of asymptomatic vibrio cholerae, salmonella enterica serovar typhi and entamoeba histolytica enteric pathogens during HIV infection and exposure.
(2017)
Background
Asymptomatic infection by enteric pathogens has been attributed to causing several outbreaks in the
world. Common pathogens in this category are Vibrio cholerae, Salmonella typhi and Entamoeba
histolytica ...
Molecular dynamics study of HIV-1 protease inhibitors and their effects on the flap dynamics of the HIV-1 subtype-C (C-SA).
(2018)
The aspartyl protease human immunodeficiency virus type 1 (HIV-1) is a 99-amino acid-long homodimer responsible for processing the Gag and Gag-Pol polyproteins into functional constituent proteins necessary for development ...
Mechanistic insights and in silico studies on selected G protein-coupled receptors implicated in HIV and neurological disorders.
(2021)
G protein-coupled receptors (GPCRs) are the largest membrane protein receptor superfamily
involved in a wide range of physiological processes. GPCRs form the major class of drug
targets for a diverse array of pathophysiological ...
Awareness, attitudes, and experiences of patients taking antiretrovirals towards adverse drug reactions at a public health facility in KwaZulu-Natal.
(2020)
Adverse drug reactions (ADRs) are undesirable side effects that occur even when a drug is
administered at the proper dose and correctly for an appropriate indication. Given the high
prevalence of Human Immuno-deficiency ...
Quantum plasmonic sensing with application to HIV research.
(2020)
The main goal of this thesis is to show how the use of quantum states of light in biosensing
with surface plasmon resonance (SPR) gives an enhancement over using classical
states. SPR is a highly sensitive technique for ...