Masters Degrees (Pharmaceutical Sciences)
Recent Submissions
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Cost-analysis of Misoprostol and Mifepristone versus Misoprostol and Methotrexate when used for medical termination of pregnancy in women of gestational age of 7 weeks and less at Embhuleni Hospital in Elukwatini, Mpumalanga.
(2019)Background: The purpose of the Republic of South Africa Choice on Termination of Pregnancy Act 92 of 1996 is to provide a safe and effective alternative to the rife illegal abortions taking place in South Africa. ... -
Knowledge, attitudes and practices of veterinarians on antibiotic use, resistance and its containment in South Africa.
(2021)The inappropriate use of antibiotics in the veterinary sector has led to antibiotic resistance (ABR), which negatively impacts animal health and welfare and indirectly on human health. Understanding the knowledge, ... -
Awareness, attitudes, and experiences of patients taking antiretrovirals towards adverse drug reactions at a public health facility in KwaZulu-Natal.
(2020)Adverse drug reactions (ADRs) are undesirable side effects that occur even when a drug is administered at the proper dose and correctly for an appropriate indication. Given the high prevalence of Human Immuno-deficiency ... -
Development of a tool to assess knowledge, awareness and perception of prostate cancer amongst women in Ghana.
(2020)Background and Objectives: The incidence of prostate cancer in developing countries is less than 30%, yet it has the disease's highest mortality. To address the mortality, strategies to increase awareness of the disease ... -
Retail pharmacy prescription medicines availability, prices, and affordability in Eswatini.
(2021)Background: The low availability of medicines in public health outlets coupled with unaffordable prices in the private sector can be a major barrier to medicines’ access. Patients in Eswatini may be forced to buy medicines ... -
Functional and molecular changes associated with intranasal buprenorphine in a healthy rodent model.
(2020)Opioid addiction is a spiralling global epidemic associated with intense drug craving and the compulsive use of opiate drugs such as heroin, oxycodone, oxymorphone amongst others. Buprenorphine (BUP), commercially available ... -
Molecular epidemiology of antibiotic-resistant Enterococcus spp. from farm-to-fork in intensive pig production in KwaZulu-Natal, South Africa.
(2021)Background: Substantial antibiotic use and high population densities in intensive farming systems results in the emergence and spread of antibiotic-resistant commensals and pathogens. This study investigated the molecular ... -
Molecular epidemiology of carbapenem-resistant Enterobacterales colonization in an intensive care unit.
(2021)Background: Due to the high association with mortality and morbidity, carbapenem-resistant Enterobacterales (CRE) in general, and carbapenem-resistant Klebsiella pneumoniae, in particular, have been listed as high-priority ... -
The effects of naringenin on oxidative stress parameters in cardiac muscles of diabetic rats.
(2019)Introduction: Diabetic cardiomyopathy (DCM) is defined by hypertrophy, oxidative stress, fibrosis and inflammation of the cardiac muscle. Hyperglycemia-associated oxidative stress plays an important role in the development ... -
An evaluation of knowledge, attitude and behaviour amongst patients regarding antibiotic use and misuse in South Africa.
(2020)Background: Antibiotic misuse is a global problem that presents a threat to public health. Antibiotic misuse and overuse are responsible for the increase and spread of antibiotic resistance. The community plays a fundamental ... -
In-silico investigation of CREB-binding protein on castration-resistant prostrate cancer: insight from molecular dynamic simulations and computer aided drug discovery.
(2020)Prostate cancer has evolved over the years despite various treatment and therapy. One recent threat of the prostate cancer is the Castration- Resistant Prostate Cancer (CRPC). The CRPC is an advanced form of prostate cancer. ... -
Evaluation of the pharmacodynamic effects of Ketamine on neurotransmitter levels and CREB/BDNF expression in rat brain.
(2020)Mental disorders contribute to 13% of the global burden of disease. With major depressive disorder (MDD) expected to be the most significant contributor by 2030, the economic and social impact of this burden will be ... -
Formulation of pH-responsive lipid-polymer hybrid nanoparticles for co-delivery and enhanced antibacterial activity of 18β-glycyrrhetinic acid and vancomycin against MRSA.
(2020)Background: Due to the rise in antimicrobial resistance and the challenges accompanied by conventional antibiotic dosage forms, there is a need for developing drug delivery systems that enhance, protect and potentiate the ... -
Evaluation of the use of cannabidiol in the treatment of anxiety related disorders by assessing changes in neurotransmitter levels and expression of CREB/BDNF in the rodent brain.
(2020)Anxiety and anxiety-related disorders are common psychiatric disorders that are responsible for high disease burden. The pathogenesis of anxiety involves dysfunction in the limbic brain regions including the amygdala, ... -
Antimicrobial prescribing in the surgical and medical wards at a private hospital in KwaZulu-Natal.
(2020)Background: Appropriate antimicrobial use is imperative due to the misuse of antimicrobials that has resulted in a growing burden of antimicrobial resistance. Evidence-based guidelines should be adhered to in order to ... -
Molecular modelling approaches in Parkinson’s disease: enhancing Domperidone oral availability through nanopolymers.
(2019)Parkinson’s disease is symbolized by resting tremor, rigidity, and bradykinesia caused by the loss of dopaminergic neurons in the substantia nigra, the presence of Lewy bodies, and a decent response to levodopa. However, ... -
Price, availability and affordability of antineoplastic medicines in Harare’s public and private institutions: implications for access.
(2020)Background: Antineoplastic medicines are increasingly becoming more vital in many public health setups. There has been significant progress made in terms of newer molecules since the advent of chemotherapy. Despite the ... -
Awareness and knowledge of doctors, pharmacists and nurses on adverse drug reaction reporting systems in Namibia.
(2020)Objective Reporting of adverse drug reactions (ADRs) in Namibian public health facilities is routinely done through safety yellow forms which are forwarded to the Therapeutics Information and Pharmacovigilance Centre ... -
The use and safety of antibiotic therapy in pregnant women.
(2020)Background Antibiotic therapy in pregnant women has significantly increased in the effort to reduce maternal and neonatal deaths. However, antibiotic exposure may negatively affect the developing foetus. Information on ...
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