Browsing Masters Degrees (Pharmaceutical Sciences) by Advisor "Baijnath, Sooraj."
Now showing items 1-5 of 5
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Evaluation of the pharmacodynamic effects of Ketamine on neurotransmitter levels and CREB/BDNF expression in rat brain.
(2020)Mental disorders contribute to 13% of the global burden of disease. With major depressive disorder (MDD) expected to be the most significant contributor by 2030, the economic and social impact of this burden will be ... -
Evaluation of the pharmacokinetics of ketamine for the treatment of major depressive disorder.
(2018)Recent reports have demonstrated ketamine’s potential use in the treatment of major depressive disorder (MDD), as it elicits potent antidepressant effects via a different mechanism compared to conventional antidepressants. ... -
Evaluation of the use of cannabidiol in the treatment of anxiety related disorders by assessing changes in neurotransmitter levels and expression of CREB/BDNF in the rodent brain.
(2020)Anxiety and anxiety-related disorders are common psychiatric disorders that are responsible for high disease burden. The pathogenesis of anxiety involves dysfunction in the limbic brain regions including the amygdala, ... -
Functional and molecular changes associated with intranasal buprenorphine in a healthy rodent model.
(2020)Opioid addiction is a spiralling global epidemic associated with intense drug craving and the compulsive use of opiate drugs such as heroin, oxycodone, oxymorphone amongst others. Buprenorphine (BUP), commercially available ... -
LC-MS/MS method development and validation for simultaneous quantification of first-line HIV drugs and second-line TB drugs in rat plasma.
(2018)Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection continues to be a major public health concern, worldwide. HIV infection has increased the TB incidence over the past twenty years, making it hard to ...