Biotechnology
Recent Submissions
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Isolation and characterization of diaryl ester catabolizing soil fungi.
(2019)Aromatic hydrocarbons are major organic pollutants that can persist in the environment. However, many fungi and yeasts can utilize these compounds as carbon and energy sources under aerobic conditions. Salol and benzyl ... -
Process development for biomass and lipid production from a local chlorella isolate using a miniature parallel raceway pond reactor.
(2020)Abstract available in pdf. -
The glutaredoxin/glutathione post-stress recovery system is dependent on the availability of glutathione in the cell.
(2020)The cellular response to oxidative stress involves three interconnected processes: reactive oxygen species detoxification, adaptation and repair. Glutathionylation is an adaptive response in which glutathione binds to ... -
Recombinant cathepsin L-like cysteine proteases for species-specific diagnosis of animal African trypanosomiasis.
(2019)African trypanosomiasis is a disease caused by protozoan parasites i.e. Trypanosoma spp. in livestock and humans and affects 37 sub-Saharan countries. Animal African trypanosomiasis (AAT) is known as nagana and African ... -
Molecular cloning, recombinant expression and characterisation of serine and cysteine protease inhibitors from Trichinella zimbabwensis.
(2019)Trichinellosis is a disease caused by parasitic helminths of the genus Trichinella. Infection occurs by ingestion of meat contaminated with infective Trichinella larvae. Cases of Trichinella zimbabwensis, a non-encapsulating ... -
Molecula characterization of chlamdia trachomatis isolates using sequence variation in the major outer membrane protein gene (OMP1) and evaluation of their susceptibility profile.
(2019)Chlamydia trachomatis infections are the most common bacterial sexually transmitted infections (STIs) in humans, worldwide. Due to asymptomatic nature of C. trachomatis, the need for sensitive, reliable and affordable ... -
The stabilisation of the cysteine protease of Carica papaya (papain) and the catalytic domain of the Cathepsin L-like cysteine protease of Trypanosoma congolense (TcoCATL)
(2019)Proteases play an intricate role in the numerous functions of a living organism. Proteases are responsible for the cleavage of proteins into smaller fragments by catalysing the hydrolysis of peptide bonds. The class of ... -
Investigation of multiple concurrent Human papillomavirus infections, oncogenicity, and STI co-infection as risk factors for Human immunodeficiency virus infection.
(2017)Background: Human papillomavirus (HPV) is one of the most common sexually transmitted infections (STIs) globally and a necessary factor for cervical cancer development. While HPV infection has been associated with increased ... -
Transferrin receptor-mediated gene delivery using functionalised gold nanoparticles.
(2018)Gene therapy strategies have shown their potential in treating numerous central nervous system (CNS) disorders, including highly aggressive brain cancers. Gold nanoparticles (AuNPs) are popular vectors for gene delivery, ... -
Synthesis, detection and quantification of inulooligosaccharides and fructooligosaccharides by extracellular and intracellular inulinase and fructosyltransferase enzymes isolated from coprophilous fungi.
(2018)Exploration of fungal biodiversity capable of producing fructosyltransferase and inulinase enzymes in significant amounts is crucial for the production of oligofructans. Indigenous coprophilous fungi are predominantly ... -
Study on Fusarium toxins contamination of cereal grains in Jiangsu Province, China.
(2018)Jiangsu Province is located in the transition zone from subtropical to warm temperate zone, with the characteristics of monsoon climate. The province's natural ecological conditions are suitable for the production of winter ... -
Treatment of lipid-rich wastewater using free and immobilized bioemulsifier and hydrolytic enzymes from indigenous bacterial isolates.
(2017)The production and discharge of raw and poorly treated lipid-rich wastewater increase yearly due to rapid urbanization and industrial growth. This results in severe environmental and health hazards by affecting the normal ... -
Quantification of time-dependent redox signalling in the Tpx1/Pap1 pathway in Schizosaccharomyces pombe.
(2019)Reactive oxygen species (ROS) can damage cellular components leading to cell death, but paradoxically, ROS also play essential roles in metabolism and signalling in eukaryotic cells. Dysregulation of this balance is ... -
Isolation and evaluation of autochthonous microalgae strains for biodiesel production and wastewater treatment.
(2018)The current depletion of global fossil fuel reserves and increasing CO2 emission are generating global climate change concerns hence, the increasing calls for the development of renewable biofuels with low CO2 emission. ... -
Methylation profiling and validation of candidate tDMRs for identification of human blood, saliva, semen and vaginal fluid and its application in forensics.
(2017)Identification of body fluids and tissues is an essential step in forensic investigation because it can be used as strong evidence in identifying suspects and victims. Currently in forensic investigations, catalytic, ... -
Expression and evaluation of a 297-amino acid fragment of the blood stage protein PfC0760c from Plasmodium falciparum.
(2019)Abstract available in pdf. -
Evaluating the effect of nitric oxide on myoblast proliferation, migration and differentiation.
(2018)Wound healing is the process of restoring tissue integrity in response to injury. This process involves four major phases namely; haemostasis, inflammation, regeneration and remodelling. These phases are regulated by ... -
Mechanisms behind the anti-diabetic effects of caffeine in a Type 2 diabetes model of rats.
(2018)Caffeine has been used for many years and is one of the most extensively consumed active food ingredient throughout the world. Caffeine has been broadly studied in a variety of areas regarding human health and performance. ... -
The endosymbiotic bacteria of the South African bird cherry-oat aphid, rhopalosiphum padi.
(2018)Cereal crops play a major role in human diet as staple foods, especially in developing countries. These crops are a part of a few edible crops that are widely cultivated globally. However, the production of these crops is ...