Browsing Masters Degrees (Physiology) by Advisor "Dutton, Michael Francis."
Now showing items 1-9 of 9
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The cytotoxic effects of T-2 toxin on normal human lymphocytes.
(1998)T -2 toxin is an immunosuppressive mycotoxin that has been conjoined with several symptoms and diseases as early as the turn of the century, but whose mechanisms of action are still being investigated. Accordingly, this ... -
A cytotoxic evaluation of aflatoxin B1, zearalenone and their epoxide derivatives using human cell lines.
(1996)Since the discovery of mycotoxins in food, the thrust of biochemical and toxicological research has been carried out on animals which has proven to be uncoordinated and not easily extrapolated to humans. Over the last ... -
Determination of exposure of humans to selected mycotoxins with particular reference to aflatoxins.
(1995)Mycotoxins are poisonous secondary metabolites commonly produced by fungi and are involved in human disease conditions known as mycotoxicoses. There is evidence to show that food eaten by the rural Black population of ... -
Development and application of an ELISA method of analysis for fumonisins
(2000)Fumonisins, mycotoxins produced by the fungus, Fusarium moniliforme, which grows on maize, are a major worldwide agricultural problem. Consumption of contaminated maize feeds causes a wide variety of toxic effects in animals ... -
The immunocytochemical and electrophoretic localisation of aflatoxin B1-binding proteins in isolated liver mitochondria.
(1998)Mitochondria perform functions which are central to the life of most eukaryotic cells. These organelles can be considered the ultimate energy power house of a living cell. The role of mitochondria in cancer phenotype remains ... -
Mycotoxins in food with particular reference to fumonisin B1 : their health impact on a Kranskop rural community, KwaZulu Natal.
(1998)The use of the multi-mycotoxin screen based on dialysis to analyze foods and feeds for mycotoxins, is well documented. This study investigated the possibility of incorporating FB I into the screen. Maize meal (25g) was ... -
The occurrence and detection of aflatoxin-macromolecular conjugates in humans.
(1998)Aflatoxin Bi (AFBi), a highly toxic fungal metabolite (mycotoxin) of certain strains of Aspergillus, has long been known to be carcinogenic in animal species. Accumulation of epidemiological evidence led to its classification, ... -
Quantitative determination of fumonisin B1 in biological material.
(1999)The mycotoxin, fumonisin B1 is produced by the mould Fusarium moniliforme, a common contaminant of maize and maize products. Small doses (mg/kg) of ingested fumonisin B1 have been shown to cause diseases and even death in ...