Masters Degrees (Paediatrics and Child Health)
Recent Submissions
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Outcomes of elective surgical patients admitted to a tertiary Paediatric Intensive Care Unit.
(2021)Background: A paediatric intensive care unit (PICU) is a unit for critically ill medical and surgical children. It is imperative that the spectrum and outcome of elective surgical patients is reviewed to help develop ... -
Evaluation of an exclusive breastfeeding promotion programme in an informal settlement in Durban.
(2002)Abstract available in PDF. -
Validation of bioimpedance against isotope methods for the determination of body composition in HIV infected South African children.
(2010)Abstract available in PDF. -
The role of parenteral phenobarbitone in the treatment of neonatal hyperbilirubinaemia.
(1993)Abstract available in PDF. -
Assessing reported adherence to antiretroviral therapy using the method of verbal recall in children from Kwa-Zulu Natal, South Africa.
(2017)Sub-Saharan Africa has the highest number of children living with HIV. HIV is one of the major causes of under-five mortality in Africa. Antiretroviral therapy in the paediatric population has improved mortality, led to a ... -
Comparison of virological responses of children commenced on an abacavir versus stavudine based antiretroviral regimen at King Edward VIII Hospital : Durban.
(2016)Background: UNAIDS estimated that in 2014 just over 160 000 children in South Africa were receiving HAART, accounting for 20% of the global HAART cohort. Finding the appropriate HAART regimen that is safe, well tolerated ... -
The accuracy, sensitivity and specificity of rapid point-of-care testing for CD4+ T cell count enumeration and TB diagnosis.
(2014)Objectives: The PIMA CD4+ T cell count analyser has been favourably evaluated for use in point-of-care (POC) situations in Mozambique and Zimbabwe, has also been recommended by the World Health Organisation (WHO), however, ... -
Innate immune mechanisms in limiting HIV-1 pathogenesis among South African adults and mother-infant pairs.
(2012)This study was conducted to investigate the role of natural killer cell surface receptors, KIRs and their cognate HLA ligands in preventing HIV-1 acquisition and disease progression in HIV-1 exposed infants. Using DBS ... -
The association of early neonatal feeding on clinical outcomes and cytotoxic T lymphocyte (CTL) responses in HIV exposed low birth weight infants.
(2011)BACKGROUND Sub-saharan Africa remains to date at the forefront of the HIV/AIDS epidemic. Despite breastfeeding being a significant mode of postnatal HIV transmission it remains the main nutritional source and pillar of ... -
The role of HLA-C restricted CD8+T cell responses in the control of HIV replication.
(2010)Certain HLA-B-restricted CD8+ T cell responses are associated with control of viremia whereas HLA-Cw* restricted responses, including Gag epitopes are associated with high viremia. To better understand the role of ... -
Transmission rates of HIV-1 and the mortality rate in high risk infants exposed to HIV, in the PMTCT programme, at the Neonatal Unit, of King Edward VIII Hospital , Durban, South Africa.
(2012)Introduction. Previous studies have established that infants born to mothers with advanced HIV disease and co-infections are smaller, premature and have rapidly progressive HIV disease and an early death. King Edward ... -
Optimum timing for vitamin A supplementation in children with diarrhoea.
(2001)Vitamin A has well recognised benefits for the reduction in severity of diarrhoeal episodes but the impact of therapeutic doses given during diarrhoea on the biochemical and clinical outcomes is less clear. In this study ... -
Investigation into optimal amikacin dosing in children.
(1996)Aminoglycoside antibacterial agents, such as amikacin, continue to play an important role in the treatment of Gram-negative infections. However, although extremely effective, they are not without potential adverse events, ... -
HIV-1 specific T-Cell responses in chronic HIV infected children during continuous treatment and structured treatment interruptions (STI).
(2010)BACKGROUND Sub-Saharan Africa has the highest number of HIV-infected individuals and limited treatment programs. The use of Highly Active Antiretroviral Therapy (HAART) has resulted in a considerable decrease in morbidity ... -
The effect of corticosteroid therapy on growth in Black South African children with nephrotic syndrome.
(1986)The most useful drugs in the management of nephrotic syndrome are the corticosteroids. These drugs are as well known for their adverse effects as they are for their therapeutic advantages. The two most common paediatric ... -
Aids for the early diagnosis of tuberculous meningitis (TBM)
(1985)Mortality and morbidity rates associated with tuberculous meningitis (TBM) are substantial. The average duration of the untreated disease from onset to death is about 17 days. The prognosis of TBM is known to correlate ...
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