V2-directed vaccine-like antibodies from HIV-1 infection identify an additional K169-binding light chain motif with broad ADCC activity.
Date
2018
Authors
van Eeden, Charmaine.
Wibmer, Constantinos Kurt.
Scheepers, Cathrine.
Richardson, Simone I.
Nonyane, Molati.
Lambson, Bronwen Elizabeth.
Mkhize, Nonhlanhla N.
Vijayakumar, Balakrishnan.
Sheng, Zizhang.
Stanfield-Oakley, Sherry.
Journal Title
Journal ISSN
Volume Title
Publisher
Cell Press.
Abstract
Abstract available in pdf.
Description
CAPRISA, 2018.
Keywords
ADCC., CAP228., CH58., ED motif., HIV., K169., RV144 vaccine response., V2 antibodies., V2 structure., Antibody evolution.
Citation
van Eeden, C., Wibmer, C.K., Scheepers, C., Richardson, S.I., Nonyane, M., Lambson, B., Mkhize, N.N., Vijayakumar, B., Sheng, Z., Stanfield-Oakley, S., Bhiman, J.N., Bekker, V., Hermanus, T., Mabvakure, B., Ismail, A., Moody, M.A., Wiehe, K., Garrett, N., Abdool Karim, S.S., Dirr, H., Fernandes, M.A., Sayed, Y., Shapiro, L., Ferrari, G., Haynes, B.F., Moore, P.L. and Morris, L. 2018. V2-directed vaccine-like antibodies from HIV-1 infection identify an additional K169-binding light chain motif with broad ADCC activity. Cell Reports 25(11), 3123-3135.