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Cooperation between strain-specific and broadly neutralizing responses limited viral escape and prolonged the exposure of the broadly neutralizing epitope.

Abstract

Abstract available in pdf.

Description

CAPRISA, 2017.

Keywords

N332 glycan., V3-glycan supersite., Broadly neutralizing antibodies., Deep sequencing., Glycan holes., Glycan shield., Helper/cooperating NAb responses., Neutralization escape., Viral escape.

Citation

Anthony, C., York, T., Bekker, V., Matten, D., Selhorst, P., Ferreria, R.C., Garrett, N.J., Abdool Karim, S.S., Morris, L., Wood, N.T., Moore, P.L. and Williamson C. 2017. Cooperation between strain-specific and broadly neutralizing responses limited viral escape and prolonged the exposure of the broadly neutralizing epitope. Journal of virology 91(18), e00828-17.

DOI