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Comparing early treatment outcomes of MDR-TB in a decentralised setting with a centralised setting in KwaZulu-Natal, South Africa.

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dc.contributor.authorLoveday, Marian Patricia.
dc.contributor.authorWallengren, Kristina.
dc.contributor.authorVoce, Anna Silvia.
dc.contributor.authorMargot, Bruce.
dc.contributor.authorReddy, T.
dc.contributor.authorMaster, Iqbal.
dc.contributor.authorBrust, James C. M.
dc.contributor.authorChaiyachati, K.
dc.contributor.authorPadayatchi, Nesri.
dc.date.accessioned2013-06-19T08:21:35Z
dc.date.available2013-06-19T08:21:35Z
dc.date.created2012
dc.date.issued2012
dc.description.abstractSetting—In KwaZulu-Natal, South Africa, a TB and HIV endemic setting, prolonged hospitalisation for the treatment of the growing number of MDR-TB patients is not possible or effective. Objective—We compared early treatment outcomes in patients with MDR-TB, with and without HIV co infection, at a central, urban, referral hospital with four decentralised rural sites. Design—This is an operational, prospective cohort study of patients between 1 July 2008 to 30 November 2009, where culture conversion, time-to-culture-conversion, survival and predictors of these outcomes were analysed. Results—Of the 860 patients with MDR-TB, 419 were at the decentralised sites and 441 at the central hospital. Overall, 71% were HIV co-infected.en
dc.identifier.citationLoveday, M. et al. 2012. Comparing early treatment outcomes of MDR-TB in a decentralised setting with a centralised setting in KwaZulu-Natal, South Africa. Int J Tuberc Lung Dis. 16(2) pp. 209–215.en
dc.identifier.issn1027-3719
dc.identifier.urihttp://dx.doi.org/10.5588/ijtld.11.0401.en
dc.identifier.urihttp://hdl.handle.net/10413/9162
dc.language.isoenen
dc.publisherInternational Union against Tuberculosis and Lung Disease.en
dc.subjectMultidrug-resistant tuberculosis--Treatment.en
dc.subjectMultidrug-resistant tuberculosis--KwaZulu-Natal.en
dc.subjectHIV infections--Complications.en
dc.subject.otherCoinfection.en
dc.subject.otherTuberculosis-HIV co-infected patients.en
dc.titleComparing early treatment outcomes of MDR-TB in a decentralised setting with a centralised setting in KwaZulu-Natal, South Africa.en
dc.typePeer reviewed journal articleen

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